Edema palpebral secundario a leishmaniasis cutánea / Eyelid oedema secondary to cutaneous leishmania

No disponible

Estudio de los bordes de resección en la cirugía conservadora del cáncer de mama. Experiencia en el Hospital de Barbastro / No disponible

Introducción: El objetivo de este estudio es determinar laamplitud del margen obtenido y la tasa de recidiva local en loscarcinomas de mama operados en el hospital de Barbastrocon cirugía conservadora entre 1989 y 2003.Material y métodos: Se han incluido 141 casos, 119 invasoresy 22 intraductales. El margen se ha definido como positivocuando se hallaba afectado por células tumorales, cercanosi era ≤ 1 mm y libre si era > 1 mm. Se evaluó preferentementemediante estudio macroscópico intraoperatorio.Resultados: La media de la edad fue de 57,36 ± 12,32años, del tamaño tumoral 14,7 ± 0,83 mm y del seguimiento86,05 ± 32,62 meses. El margen resultó positivo en 13 casos,6 reintervenidos. Los 7 restantes afectaban a la cara anteriory/o posterior y no se reintervinieron. Treinta y un casostuvieron margen cercano. Han presentado recidiva local ipsilateral3 carcinomas infiltrantes.Conclusiones: El 73% de los casos tienen bordes libres.Nuestra tasa de recidiva local, tras una media de seguimientode 86 meses, es baja (2%). La afectación de las caras anteriory posterior no ha ocasionado recidiva y creemos que deberíanvalorarse de forma diferente al resto de los márgenes(AU)

Objective: The aim of this study was to analyze the tumormargindistance and the local recurrences of breast cancer casestreated at the Hospital of Barbastro with breast-conservingtherapy between 1989 and 2003.Patients and method: 141 cases are included, 119 invasiveand 22 intraductal carcinomas. Margin was defined aspositive when tumor cells where in contact with india ink,close if ≤ 1 mm and free if > 1 mm. A macroscopic intraoperativeassessment of margin was carried out mainly.Results: The mean age was 57,36 ± 12,32, the mean tumorsize 14,7 ± 0,83 mm and the mean follow-up 86,05 ±32,62 months. The final margin was positive in 13 cases witha need for reintervention in 6 of them. The remaining 7, affectinganterior and/or posterior surfaces, were not operated.The distance was ≤ 1 mm in 31 cases. Local recurrences havebeen found in 3 invasive ipsilateral carcinomas.Conclusion: A free margin was found in 73% of cases. Localrecurrence rate is low (2%) after a median follow-up of 86months. Involvement of anterior and posterior surfaces hasnot been cause of recurrences. Thus it seems they should beassessed in different way to the others(AU)

[Descriptive study of cervical intraepithelial neoplasia grade III (CIN III) cases in the area of the hospital of Barbastro]. / Estudio descriptivo de los casos de neoplasia intraepitelial grado III (CIN III) en el área del Hospital de Barbastro.

OBJECTIVE: A description of early diagnosis of cervical cancer in the Barbastro Hospital area. DESIGN: Descriptive and retrospective study on all the CIN III cases collected in the Tumor Hospital Registry from 1989 to 1998. To correlate the data to the population covered by the hospital. PARTICIPANTS AND METHODS: 59 CIN III cases were detected and 16 invasive cancers. The total smears studied were 31409. The population covered was 50220 women, 15% of whom are between the age of 35 and 64. RESULTS: The frequency of CIN III was 12 cases per 100000 women and year and of invasive cancers 3.2. From 59 CIN III 20 belong to the first five-year period and 39 to the second. The mean age was 37 12 (20-82). No significant statistical differences were found between five-year periods. The most frequent decade was 30-39 years (50% of cases). 10489 smears were studied from the first five-year period and 20911 from the second. 75% of invasive cases did not come from screening. CONCLUSIONS: The tendency is that when the number of screened smears increases so does the number of CIN III. The frequency of the preneoplastic disease and invasive cancer is low. Therefore, close coordination between hospital departments of gynaecology and pathology together with primary health care is vital in order to extend the coverage, to reach risk groups and rationalise the screening of cervical cancer.

Estudio descriptivo de los casos de neoplasia intraepitelial grado III (CIN III) en el área del Hospital de Barbastro / Descriptive study of cervical intraepithelial neoplasia grade III (CIN III) cases in the area of the Hospital of Barbastro

Objetivo. Conocer la situación del diagnóstico precoz del cáncer de cérvix en el área del Hospital de Barbastro. Diseño. Estudio descriptivo retrospectivo de todos los casos de CIN III recogidos en el Registro de Tumores Hospitalario desde 1989 a 1998. Comparación con los diagnósticos citológicos de CIN I y II anuales y con los de cáncer invasor. Correlación con los datos de la población atendida. Participantes y métodos. El número de CIN III detectados ha sido de 59 y el de cánceres invasores, 16. El total de citologías estudiadas ha sido de 31.409. El hospital atiende una población de 50.220 mujeres, de las que un 15 por ciento tiene 35-64 años. Resultados. La frecuencia de CIN III es de 12 casos por 100.000 mujeres y año y la de cáncer invasor de 3,2. Los 59 casos de CIN III se han repartido 20 en el primer período y 39 en el segundo. La edad media fue de 37 ñ 12 (20-82) y no ha presentado diferencias significativas en ambos quinquenios. La década con mayor frecuencia de casos (50 por ciento) fue la de 30-39 años. Se estudiaron 10.489 citologías en el primer quinquenio y 20.911 en el segundo. Un 75 por ciento de los cánceres invasores no provenía del cribado. Conclusiones. Existe una tendencia a aumentar el número de casos detectados de CIN III cuando lo hace el número de citologías examinadas. La frecuencia de la enfermedad preneoplásica y del cáncer invasor es baja. La coordinación de los servicios hospitalarios de ginecología y anatomía patológica con los de atención primaria es básica para ampliar la cobertura, llegar a los grupos de riesgo y racionalizar el cribado del cáncer de cérvix. (AU)

Gastric carcinoid tumour. A clinicopathologic and immunohistochemical study of four cases.

Over the last decade a great increase in the frequency of Gastric Carcinoid Tumours has been detected being considered by some authors as the most frequent digestive carcinoid. These have been divided into three types: I) those associated with chronic atrophic gastritis; II) associated with Zollinger-Ellison syndrome, and III) sporadic lesions. We present four cases of gastric carcinoid type I (3 women and 1 man) two of them associated with pernicious anemia and another two with iron deficiency anemia. Three patients were operated upon, and an endoscopy removal was carried out on the fourth patient. The clinical course has been favourable during the follow-up. Multiple lesions were detected in 3 patients, with tumours less than 2 cm in size, except for a 4.5 cm polyp, which invaded the submucous layer. This case presented carcinoid syndrome without evidence of liver metastasis. Argyrophilia. Chromogranin A and Neuronal Specific Enolase tintions were located in the tumor and in the hyperplastic endocrine cells of the mucous.

[Suprarenal myelolipoma: an infrequent cause of acute abdomen]. / Mielolipoma suprarrenal: causa infrecuente de abdomen agudo.

Adrenal myelolipoma is a benign tumor associated with chronic disease and a long survival after surgical exeresis. It is scarcely symptomatic and only exceptionally has an acute onset, wherein lies the interest of this report.